Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | WNT3 | P56703 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719437 | 0.86 | TSHR (0.43) | ALOX15TSHRHSD17B10NAMPTALDH1A1 | |
| SCHEMBL2719435 | 0.86 | TSHR (0.43) | ALOX15TSHRHSD17B10NAMPTALDH1A1 | |
| SCHEMBL6011965 | 0.85 | MAOB (0.43) | ALOX15TSHRHSD17B10NAMPTALDH1A1 | |
| SCHEMBL2718627 | 0.85 | ALDH1A1 (0.53) | ALOX15TSHRHSD17B10NAMPTALDH1A1 | |
| SCHEMBL6011042 | 0.85 | ALDH1A1 (0.53) | ALOX15TSHRHSD17B10NAMPTALDH1A1 | |
| SCHEMBL2718621 | 0.85 | ALDH1A1 (0.53) | ALOX15TSHRHSD17B10NAMPTALDH1A1 | |
| SCHEMBL14261838 | 0.85 | ALOX15 (0.40) | ALOX15TSHRHSD17B10NAMPTALDH1A1 | |
| SCHEMBL10069075 | 0.83 | MAPT (0.47) | ALOX15TSHRHSD17B10NAMPTALDH1A1 | |
| SCHEMBL14261804 | 0.82 | NPC1 (0.46) | ALOX15TSHRHSD17B10NAMPTALDH1A1 | |
| SCHEMBL14261824 | 0.81 | HTT (0.47) | ALOX15TSHRHSD17B10NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1785415-B1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |