SCHEMBL6011815

SCHEMBL6011815

O=C(CCCBr)CCCCBr

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
LMNA P02545 3/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FAAH O00519 2/20 0.35
TSHR P16473 3/20 0.35
NFKB1 P19838 1/20 0.33
PMP22 Q01453 1/20 0.33
FOLH1 Q04609 1/20 0.33
ACE P12821 1/20 0.32
HAO1 Q9UJM8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1166742 0.97 KMT2A (0.40) KMT2AMAPTLMNAKDM4EMEN1
SCHEMBL11553771 0.94 MAPT (0.44) KMT2AMAPTLMNATDP1FAAH
SCHEMBL540009 0.94 LMNA (0.39) KMT2AMAPTLMNAKDM4EMEN1
SCHEMBL3218037 0.88
SCHEMBL3227163 0.85
SCHEMBL11343890 0.85
SCHEMBL11245058 0.84 TSHR (0.60) KMT2AMAPTLMNAMEN1ALDH1A1
SCHEMBL28466238 0.82 FAAH (0.52) KMT2AMAPTLMNAKDM4EMEN1
SCHEMBL14284057 0.82 TSHR (0.38) KMT2AMAPTLMNATDP1FAAH
SCHEMBL14284065 0.82 TSHR (0.38) KMT2AMAPTLMNATDP1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060115695-A1 Bisphenol compound and aromatic polyaryl ether UBE INDUSTRIES, LTD. (JP) 2006-06-01 US disclosed
EP-0431605-A2 1-Azabicyclo[m.n.O]alkane derivatives, their salts and process for preparing them SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1991-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060115695-A1 Bisphenol compound and aromatic polyaryl ether ARSA, EP300, PAH KMT2A 505/4885MAPT 4080/4885LMNA 2658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.