Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142357 | 0.90 | POLB (0.57) | TMPRSS4EPHX2POLBKMT2AP2RX1 | |
| SCHEMBL7933590 | 0.86 | TMPRSS4 (0.53) | TMPRSS4EPHX2POLBKMT2AP2RX1 | |
| SCHEMBL5031966 | 0.86 | LMNA (0.56) | TMPRSS4EPHX2POLBKMT2AP2RX1 | |
| SCHEMBL4763294 | 0.82 | TMPRSS4 (0.57) | TMPRSS4EPHX2POLBKMT2AP2RX1 | |
| SCHEMBL27347635 | 0.76 | TMPRSS4 (0.45) | TMPRSS4EPHX2POLBKMT2AP2RX1 | |
| SCHEMBL14520815 | 0.76 | TMPRSS4 (0.52) | TMPRSS4EPHX2POLBKMT2AP2RX1 | |
| SCHEMBL5474295 | 0.76 | TMPRSS4 (0.52) | TMPRSS4EPHX2POLBKMT2AP2RX1 | |
| SCHEMBL5474298 | 0.76 | TMPRSS4 (0.52) | TMPRSS4EPHX2POLBKMT2AP2RX1 | |
| SCHEMBL95510 | 0.76 | NPC1 (0.59) | TMPRSS4EPHX2KMT2AP2RX1HDAC3 | |
| SCHEMBL17671260 | 0.75 | HDAC3 (0.53) | TMPRSS4EPHX2POLBKMT2AP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626964-A2 | NEW BENZIMIDAZOLE DERIVATIVES | AstraZeneca AB (SE) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004100865-A2 | NEW BENZIMIDAZOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-11-25 | — | — | WO | disclosed |