SCHEMBL27347635

SCHEMBL27347635

[CH2]CC(OC(=O)Nc1cc(OC)cc(C(F)(F)F)c1)C(=C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TMPRSS4 Q9NRS4 2/20 0.45
EPHX2 P34913 1/20 0.45
P2RX1 P51575 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
CCR2 P41597 1/20 0.39
MAPT P10636 2/20 0.39
SLC13A3 Q8WWT9 1/20 0.38
TRPA1 O75762 1/20 0.38
KMT2A Q03164 2/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
POLB P06746 1/20 0.37
XPO1 O14980 1/20 0.37
RAF1 P04049 1/20 0.37
BRAF P15056 1/20 0.37
S1PR2 O95136 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835063 0.83 TMPRSS4 (0.46) TMPRSS4EPHX2P2RX1HDAC3HDAC1
SCHEMBL6011964 0.76 TMPRSS4 (0.53) TMPRSS4EPHX2P2RX1HDAC3HDAC1
SCHEMBL4763294 0.76 TMPRSS4 (0.57) TMPRSS4EPHX2P2RX1HDAC3HDAC1
SCHEMBL5142357 0.75 POLB (0.57) TMPRSS4EPHX2P2RX1HDAC3HDAC1
SCHEMBL9837072 0.73 MAPT (0.46) TMPRSS4P2RX1MAPTSLC13A3TRPA1
SCHEMBL5031966 0.71 LMNA (0.56) TMPRSS4EPHX2P2RX1HDAC3HDAC1
SCHEMBL7933590 0.71 TMPRSS4 (0.53) TMPRSS4EPHX2P2RX1HDAC3HDAC1
SCHEMBL1012287 0.71 ALDH1A1 (0.57) TMPRSS4EPHX2P2RX1MAPTTRPA1
SCHEMBL5474298 0.70 TMPRSS4 (0.52) TMPRSS4EPHX2P2RX1HDAC3HDAC1
SCHEMBL5474295 0.70 TMPRSS4 (0.52) TMPRSS4EPHX2P2RX1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed