Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261857 | 0.89 | MAOB (0.50) | MAOBNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL6011966 | 0.87 | MAOB (0.52) | MAOBNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL6011774 | 0.85 | ALDH1A1 (0.53) | MAOBNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10069270 | 0.85 | MAOB (0.50) | MAOBNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL14261840 | 0.82 | GPR119 (0.48) | MAOBNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6011718 | 0.81 | MAOB (0.53) | MAOBNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL10069713 | 0.81 | ALDH1A1 (0.49) | MAOBNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14261826 | 0.81 | MAOB (0.44) | MAOBNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL10068861 | 0.81 | MAOB (0.44) | MAOBNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL14261822 | 0.80 | TSHR (0.48) | MAOBNPC1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1785415-B1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |