Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | WNT3 | P56703 | 1/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011036 | 0.91 | ALOX15 (0.50) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL6011748 | 0.88 | MAOB (0.50) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL2718661 | 0.88 | MAOB (0.50) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL14261828 | 0.88 | MAOB (0.50) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL6011051 | 0.88 | ALOX15 (0.48) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL14261815 | 0.88 | MAOB (0.50) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL6011774 | 0.88 | ALDH1A1 (0.53) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL2718666 | 0.88 | MAOB (0.50) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL6012034 | 0.88 | MAOB (0.50) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL10069198 | 0.88 | TSHR (0.50) | TSHRALOX15HSD17B10NAMPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1785415-B1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |
| EP-1785415-A1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Astellas Pharma Inc. (JP) | 2007-05-16 | — | — | EP | disclosed |