Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052925 | 1.00 | MEN1 (0.53) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL3052928 | 1.00 | MEN1 (0.53) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL5152176 | 0.89 | NPC1 (0.47) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL5152168 | 0.89 | NPC1 (0.47) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL28466920 | 0.88 | MEN1 (0.43) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL31019026 | 0.88 | MEN1 (0.43) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL22852306 | 0.88 | MEN1 (0.43) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL22745294 | 0.87 | NPSR1 (0.49) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL7487281 | 0.86 | GPR119 (0.47) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL5849203 | 0.86 | GPR119 (0.47) | MEN1KMT2ALMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578777-A4 | IAP BINDING COMPOUNDS | UNIV PRINCETON (US) | 2006-08-16 | — | — | EP | disclosed |
| EP-1578777-A2 | IAP BINDING COMPOUNDS | The Trustees of Princeton University (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004007529-A2 | IAP BINDING COMPOUNDS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2004-01-22 | — | — | WO | disclosed |