Hydroquinone

Hydroquinone

SCHEMBL6012111

NN.Oc1ccc(O)cc1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.80
CA1 P00915 4/20 0.80
CA2 P00918 4/20 0.80
CA9 Q16790 4/20 0.80
ALOX15 P16050 3/20 0.80
CA3 P07451 3/20 0.80
CA14 Q9ULX7 3/20 0.80
ALDH1A1 P00352 3/20 0.80
CYP3A4 P08684 2/20 0.80
HIF1A Q16665 2/20 0.80
HSD17B10 Q99714 2/20 0.80
MEN1 O00255 2/20 0.80
LMNA P02545 2/20 0.80
CA4 P22748 2/20 0.80
KMT2A Q03164 2/20 0.80
KDM4E B2RXH2 2/20 0.80
NPC1 O15118 1/20 0.80
GMNN O75496 1/20 0.80
MAPT P10636 1/20 0.80
TYR P14679 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL28468106 0.90 CA2 (0.80) CA12CA1CA2CA9ALOX15
Hydroquinone SCHEMBL11511669 0.89 ALOX15 (1.00) CA12CA1CA2CA9ALOX15
Hydroquinone SCHEMBL15516 0.89
Hydroquinone SCHEMBL460669 0.89 ALOX15 (1.00) CA12CA1CA2CA9ALOX15
Hydrazine SCHEMBL29067366 0.88 ESR1 (0.85) CA12CA1CA2CA9ALOX15
Hydroquinone SCHEMBL27813899 0.86 CYP3A4 (0.73) CA12CA1CA2CA9ALOX15
Hydroquinone SCHEMBL6259933 0.86 CYP3A4 (0.73) CA12CA1CA2CA9ALOX15
Hydroquinone SCHEMBL11758857 0.86 CYP3A4 (0.73) CA12CA1CA2CA9ALOX15
Hydroquinone SCHEMBL8680894 0.84
Hydroquinone SCHEMBL11552027 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240158351-A1 S6K1 PROTEIN KINASE INHIBITORS AS CANCER THERAPEUTICS XAVIER UNIVERSITY OF LOUISIANA 2024-05-16 US disclosed
US-11912660-B2 S6K1 protein kinase inhibitors as cancer therapeutics XAVIER UNIVERSITY OF LOUISIANA (US) 2024-02-27 US disclosed
US-20210323919-A1 S6K1 PROTEIN KINASE INHIBITORS AS CANCER THERAPEUTICS XAVIER UNIVERSITY OF LOUISIANA 2021-10-21 US disclosed
US-7074959-B2 Methods and systems for remediating hydrazine-contaminated equipment and/or surfaces NEW MEXICO HIGHLANDS UNIVERSITY (US) 2006-07-11 US disclosed
US-6955706-B2 Liquid degassing system for power plant system layup DOMINION ENGINEERING INC (US) 2005-10-18 US disclosed
US-20040025696-A1 Liquid degassing system for power plant system layup BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2004-02-12 US disclosed
US-20040024251-A1 Methods and systems for hydrazine remediation HELVENSTON MERRITT C (US) 2004-02-05 US disclosed
WO-2003086573-A1 LIQUID DEGASSING SYSTEM FOR POWER PLANT SYSTEM LAYUP DOMINION ENGINEERING, INC. (US) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210323919-A1 S6K1 PROTEIN KINASE INHIBITORS AS CANCER THERAPEUTICS RPS6KA6, RPS6KA1, RPS6KA3 CA12 4718/4885CA1 4839/4885CA2 4437/4885
US-11912660-B2 S6K1 protein kinase inhibitors as cancer therapeutics RPS6KA6, RPS6KA1, RPS6KA3 CA12 4718/4885CA1 4839/4885CA2 4437/4885
US-20240158351-A1 S6K1 PROTEIN KINASE INHIBITORS AS CANCER THERAPEUTICS RPS6KA6, RPS6KA1, RPS6KA3 CA12 4718/4885CA1 4839/4885CA2 4437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.