Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | PRPS1 | P60891 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308134 | 1.00 | DPP4 (0.43) | DPP4DPP8USP2MAPK1TDP1 | |
| SCHEMBL306877 | 0.79 | STAT3 (0.47) | LMNAADORA2BARCSNK2A1CSNK2A2 | |
| SCHEMBL14291769 | 0.79 | DPP4 (0.49) | DPP4DPP8TDP1LMNAADORA2B | |
| SCHEMBL10110183 | 0.78 | KDM4E (0.40) | USP2MAPK1AREGLN3EIF4EBP1 | |
| SCHEMBL308832 | 0.78 | DPP4 (0.58) | DPP4DPP8MAPK1TDP1LMNA | |
| SCHEMBL307334 | 0.78 | DPP4 (0.45) | DPP4DPP8TDP1LMNAADORA2B | |
| SCHEMBL3029115 | 0.78 | PRPS1 (0.51) | DPP4DPP8TDP1LMNAADORA2B | |
| SCHEMBL21486449 | 0.75 | DPP4 (0.45) | DPP4DPP8USP2MAPK1FGFR1 | |
| SCHEMBL4453299 | 0.74 | DPP4 (0.45) | DPP4DPP8TDP1LMNAADORA2B | |
| SCHEMBL3037931 | 0.74 | PRPS1 (0.54) | DPP4DPP8MAPK1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626964-A2 | NEW BENZIMIDAZOLE DERIVATIVES | AstraZeneca AB (SE) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004100865-A2 | NEW BENZIMIDAZOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-11-25 | — | — | WO | disclosed |