Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14615139 | 0.86 | GRM4 (0.42) | ROCK2 | |
| SCHEMBL23458839 | 0.86 | ROCK2 (0.53) | ROCK2RAB9A | |
| SCHEMBL20646781 | 0.84 | RAB9A (0.48) | ROCK2RAB9A | |
| SCHEMBL20646783 | 0.84 | RAB9A (0.48) | ROCK2RAB9A | |
| SCHEMBL14334921 | 0.83 | MKNK1 (0.54) | ROCK2RAB9A | |
| SCHEMBL8299116 | 0.80 | CNR2 (0.48) | RAB9A | |
| SCHEMBL14334120 | 0.79 | ROCK2 (0.48) | ROCK2 | |
| SCHEMBL6012264 | 0.79 | CNR2 (0.60) | RAB9A | |
| Hydrochloric Acid SCHEMBL4185132 | 0.79 | CNR2 (0.47) | RAB9A | |
| SCHEMBL3673425 | 0.78 | GRM4 (0.50) | ROCK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651640-A1 | NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS | Pfizer Limited (GB) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005009994-A1 | NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS | PFIZER LIMITED (GB) | 2005-02-03 | — | — | WO | disclosed |