Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932936 | 0.86 | TPMT (0.37) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL124763 | 0.83 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL29394151 | 0.83 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL6396616 | 0.81 | TSHR (0.45) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL10826112 | 0.81 | LMNA (0.39) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL6396610 | 0.79 | LMNA (0.38) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL3663229 | 0.78 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL31518592 | 0.78 | TSHR (0.39) | LMNATPMTTSHRMAPK1PARP1 | |
| SCHEMBL10495744 | 0.78 | TSHR (0.39) | LMNATPMTTSHRMAPK1PARP1 | |
| SCHEMBL9451092 | 0.77 | POLB (0.32) | TPMTTSHRMAPK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983227-B8 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | GE HEALTHCARE AS (NO) | 2006-10-25 | — | — | EP | disclosed |
| EP-0983227-B1 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2006-08-30 | — | — | EP | disclosed |
| US-RE38856-E1 | Preparation of tri-iodo benzene compounds | AMERSHAM HEALTH AS (NO) | 2005-10-25 | — | — | US | disclosed |
| US-6137006-A | IODINATING 2,4,6-UNSUBSTITUTED BENZENE RING CONTAINING COMPOUND WITH IODINE HALIDE IODINATING AGENT IN AQUEOUS REACTION MEDIUM, ADDING BASE, REDUCING AGENT AND AGITATING; ADDING SEED CRYSTALS; COOLING, PRECIPITATING REACTION PRODUCT | NYCOMED IMAGING AS (NO) | 2000-10-24 | — | — | US | disclosed |
| EP-0983227-A1 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | NYCOMED IMAGING AS (NO) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052909-A1 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | NYCOMED IMAGING AS (NO) | 1998-11-26 | — | — | WO | disclosed |
| US-4025550-A | Derivatives of triiodo-aminobenzenecarboxylic acids and the preparation thereof | CHEMIE LINZ AKTIENGESELLSCHAFT (OE) | 1977-05-24 | — | — | US | disclosed |