Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394151 | 1.00 | TSHR (0.46) | TSHRMAPK1LMNACYP2C9CHRM1 | |
| SCHEMBL6396616 | 0.98 | TSHR (0.45) | TSHRMAPK1LMNACYP2C9CHRM1 | |
| Butanedione SCHEMBL27926797 | 0.91 | LMNA (0.44) | TSHRMAPK1LMNACYP2C9CHRM1 | |
| Acrylamide SCHEMBL8663429 | 0.88 | TSHR (0.39) | TSHRMAPK1LMNACYP2C9CHRM1 | |
| Glutarate SCHEMBL11207827 | 0.88 | TSHR (0.49) | TSHRMAPK1LMNACYP2C9CHRM1 | |
| SCHEMBL377395 | 0.84 | MAPK1 (0.53) | TSHRMAPK1LMNACYP2C9CHRM1 | |
| Tetraethylene Glycol SCHEMBL11821634 | 0.83 | TSHR (0.39) | TSHRMAPK1LMNACYP2C9CHRM1 | |
| SCHEMBL31534599 | 0.83 | KDM4E (0.41) | TSHRMAPK1CYP2C9HIF1ATPMT | |
| SCHEMBL27979892 | 0.83 | TPMT (0.46) | TSHRMAPK1LMNACYP2C9CHRM1 | |
| SCHEMBL6012587 | 0.83 | LMNA (0.40) | TSHRMAPK1LMNACYP2C9CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017165-A1 | METHOXYPOLYETHYLENE GLYCOL-POLY(LACTIC-CO-GLYCOLIC ACID)-POLYLYSINE-BASED DEVELOPING POROUS MICROSPHERE, PREPARATION METHOD, AND USE | 森心(上海)科技有限公司 | 2024-01-25 | — | — | WO | claimed |
| CN-115252877-A | Iodopolyethylene glycol-polylactic glycolic acid-polylysine development porous microsphere, preparation method and application | 上海市肿瘤研究所 | 2022-11-01 | — | — | CN | claimed |
| CN-114437344-A | Room-temperature phosphorescent polyamide copolymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114057600-A | X-ray developable molecule, drug-loaded embolism microsphere and preparation method thereof | 上海汇禾医疗科技有限公司 | 2022-02-18 | — | — | CN | claimed |
| US-20210069352-A1 | IODINE-BASED PARTICLES | NANOPROBES, INC. | 2021-03-11 | — | — | US | claimed |
| CN-105194693-B | For CT imagings and the golden shell parcel iodo nano-particle of photo-thermal therapy and its preparation | 天津医科大学 | 2018-03-27 | — | — | CN | claimed |
| US-20170274101-A1 | IODINE-BASED PARTICLES | NANOPROBES, INC. | 2017-09-28 | — | — | US | claimed |
| WO-2017165841-A1 | IODINE-BASED PARTICLES | NANOPROBES, INC. (US) | 2017-09-28 | — | — | WO | claimed |
| CN-106007818-A | Full-automatic-temperature-control refuse fermentation apparatus and operating method thereof | 徐州工程学院 | 2016-10-12 | — | — | CN | claimed |
| CN-105194693-A | Golden-shell covered iodo-nanoparticle for CT imaging and photo-thermal treatment and preparation of golden-shell covered iodo-nanoparticle | UNIV TIANJIN MEDICAL | 2015-12-30 | — | — | CN | claimed |
| US-5141739-A | Delivery of x-ray contrast agents using receptor mediated endocytosis | ADVANCED MAGNETICS, INC. (US) | 1992-08-25 | — | — | US | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-114057600-B | X-ray developable molecule, drug-loaded embolism microsphere and preparation method thereof | 上海汇禾医疗科技股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117323459-A | Developable embolism microsphere and preparation method and application thereof | 至微(深圳)医学科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| US-11774853-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-10-03 | — | — | US | disclosed |
| US-4031088-A | Iodinated anilic acids | STERLING DRUG INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4031088-A | Iodinated anilic acids | STERLING DRUG INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4001298-A | RADIOPAQUE AGENTS | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3853866-A | 3-AMINO-2,4,6-TRIIODOBENZOIC ACID DERIVATIVES | CHEMIE HOLDING AKTIENGESELLSCHAFT | 1974-12-10 | — | — | US | disclosed |
| US-3853866-A | 3-AMINO-2,4,6-TRIIODOBENZOIC ACID DERIVATIVES | CHEMIE HOLDING AKTIENGESELLSCHAFT | 1974-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170274101-A1 | IODINE-BASED PARTICLES | TPO, BRI3BP, INSRR | TSHR 25/4885MAPK1 3330/4885LMNA 3921/4885 |
| US-20210069352-A1 | IODINE-BASED PARTICLES | TPO, BRI3BP, INSRR | TSHR 25/4885MAPK1 3330/4885LMNA 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.