Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | LAP3 | P28838 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426058 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LTA4HLAP3TDP1KMT2A | |
| SCHEMBL6575848 | 0.94 | ALDH1A1 (0.61) | ALDH1A1LTA4HLAP3TDP1KMT2A | |
| SCHEMBL1600361 | 0.94 | ALDH1A1 (0.61) | ALDH1A1LTA4HLAP3TDP1KMT2A | |
| SCHEMBL366832 | 0.94 | ALDH1A1 (0.61) | ALDH1A1LTA4HLAP3TDP1KMT2A | |
| SCHEMBL14066236 | 0.94 | ALDH1A1 (0.61) | ALDH1A1LTA4HLAP3TDP1KMT2A | |
| Benzyl Alcohol SCHEMBL27898646 | 0.87 | ALDH1A1 (0.53) | ALDH1A1LTA4HLAP3TDP1KMT2A | |
| SCHEMBL8424336 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LTA4HLAP3TDP1KMT2A | |
| SCHEMBL19853604 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LTA4HLAP3TDP1KMT2A | |
| SCHEMBL8424338 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LTA4HLAP3TDP1KMT2A | |
| SCHEMBL15449774 | 0.85 | ALDH1A1 (0.61) | ALDH1A1LTA4HLAP3TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621126-B | Improved ezetimibe preparation method | 重庆圣华曦药业股份有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-118307501-A | Dihydrophenanthropyrrole compound, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-07-09 | — | — | CN | disclosed |
| CN-114621126-B | Improved ezetimibe preparation method | 重庆圣华曦药业股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-114621126-A | Improved preparation method of ezetimibe | 重庆圣华曦药业股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-107759778-A | The preparation and application of a kind of polymalic acid and the high polymalic acid benzyl ester of crystallinity | 中国人民解放军第四军医大学 | 2018-03-06 | — | — | CN | disclosed |
| US-9630905-B2 | Amphiphilic macromolecules and methods of use thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-04-25 | — | — | US | disclosed |
| CN-105111272-B | 3-monouronic acid o-glycoside oleanane type and ursane type triterpenoid saponin derivative, as well as preparation method and application thereof | 中国医学科学院药用植物研究所 | 2017-03-22 | — | — | CN | disclosed |
| US-20160068467-A1 | AMPHIPHILIC MACROMOLECULES AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-03-10 | — | — | US | disclosed |
| US-7094862-B2 | Method for preparing polyesters having intrachain free acid functions | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-08-22 | — | — | US | disclosed |
| US-20040127676-A1 | Method for preparing polyesters having intrachain free acid functions | IPSEN PHARMA S.A.S. (FR) | 2004-07-01 | — | — | US | disclosed |
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| CN-1081681-A | Amino sugar derivative | DAIICHI SEIYAKU CO (JP) | 1994-02-09 | — | — | CN | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068467-A1 | AMPHIPHILIC MACROMOLECULES AND METHODS OF USE THEREOF | ZYX, APOB, MSR1 | ALDH1A1 3720/4885LTA4H 1360/4885LAP3 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.