Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614859 | 0.96 | CCR5 (0.48) | CCR5CXCR3 | |
| SCHEMBL6613108 | 0.96 | CCR5 (0.48) | CCR5CXCR3 | |
| SCHEMBL6611179 | 0.95 | CXCR3 (0.53) | CCR5CXCR3 | |
| SCHEMBL6615700 | 0.94 | CCR5 (0.51) | CCR5CXCR3 | |
| SCHEMBL6611530 | 0.94 | CCR5 (0.47) | CCR5CXCR3 | |
| SCHEMBL6611210 | 0.93 | CCR5 (0.46) | CCR5CXCR3 | |
| SCHEMBL6012485 | 0.92 | CCR5 (0.52) | CCR5CXCR3 | |
| SCHEMBL6612256 | 0.92 | CCR5 (0.47) | CCR5CXCR3 | |
| SCHEMBL6611855 | 0.92 | CCR5 (0.48) | CCR5CXCR3 | |
| SCHEMBL6612224 | 0.92 | CCR5 (0.48) | CCR5CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119091-B2 | Triazaspiro[5.5]undecane derivatives and pharmaceutical compositions comprising thereof, as an active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-10-10 | — | — | US | claimed |
| US-7285552-B2 | Drugs containing triazaspiro[5.5]undecane derivatives as the active ingredient | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-10-23 | — | — | US | disclosed |