Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 13/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550452 | 0.98 | SIRT2 (0.45) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL5550449 | 0.82 | KMT2A (0.46) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL5550454 | 0.82 | KMT2A (0.46) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL22804091 | 0.76 | FOLH1 (0.60) | SIRT2SIRT1SIRT5 | |
| SCHEMBL19017845 | 0.75 | MAPT (0.49) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL16847608 | 0.75 | MAPT (0.49) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL14123951 | 0.74 | KMT2A (0.53) | — | |
| SCHEMBL16847607 | 0.74 | MAPT (0.49) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL18100002 | 0.74 | SIRT2 (0.44) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL16093051 | 0.74 | KMT2A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718340-A2 | NEW EFFECTOR CONJUGATES, PROCESS FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | Schering AG (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005074901-A2 | NEW EFFECTOR CONJUGATES, PROCESS FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | SCHERING AG (DE) | 2005-08-18 | — | — | WO | disclosed |