Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014834 | 0.75 | TPMT (0.37) | HPGDPOLBMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9752266 | 0.75 | ALOX15 (0.49) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL6013194 | 0.74 | HPGD (0.44) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL9009216 | 0.72 | TPMT (0.43) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL29108670 | 0.71 | ALOX15 (0.48) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL14058695 | 0.71 | HPGD (0.48) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL14057967 | 0.71 | HPGD (0.48) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL7870127 | 0.70 | HPGD (0.66) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL461826 | 0.70 | HPGD (0.66) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL4559294 | 0.70 | HPGD (0.66) | HPGDCYP1A2POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983227-B8 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | GE HEALTHCARE AS (NO) | 2006-10-25 | — | — | EP | claimed |
| EP-0983227-A1 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | NYCOMED IMAGING AS (NO) | 2000-03-08 | — | — | EP | claimed |
| WO-1998052909-A1 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | NYCOMED IMAGING AS (NO) | 1998-11-26 | — | — | WO | claimed |
| EP-0983227-B8 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | GE HEALTHCARE AS (NO) | 2006-10-25 | — | — | EP | disclosed |
| EP-0983227-A1 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | NYCOMED IMAGING AS (NO) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052909-A1 | PREPARATION OF TRI-IODO BENZENE COMPOUNDS | NYCOMED IMAGING AS (NO) | 1998-11-26 | — | — | WO | disclosed |