SCHEMBL6013341

SCHEMBL6013341

N#Cc1ccc(-c2ccsc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.52
CYP2E1 P05181 2/20 0.52
CYP2B6 P20813 2/20 0.52
MMP3 P08254 1/20 0.50
ALDH1A1 P00352 2/20 0.46
KIF11 P52732 2/20 0.45
KCNH2 Q12809 1/20 0.44
CYP11B2 P19099 2/20 0.43
CYP17A1 P05093 1/20 0.43
CYP11B1 P15538 1/20 0.43
DRD3 P35462 1/20 0.43
CA12 O43570 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
CA1 P00915 1/20 0.42
GAA P10253 1/20 0.42
KDM1A O60341 1/20 0.41
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
PTGS1 P23219 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7449457 0.83 CYP2E1 (0.44) CYP2A6CYP2E1CYP2B6MMP3ALDH1A1
SCHEMBL4201985 0.81 CYP2A6 (0.50) CYP2A6CYP2E1CYP2B6ALDH1A1KCNH2
SCHEMBL27989815 0.81 CYP2A6 (0.74) CYP2A6CYP2E1CYP2B6KCNH2CYP11B2
SCHEMBL28312712 0.78 CYP2A6 (0.44) CYP2A6CYP2E1CYP2B6ALDH1A1KCNH2
SCHEMBL2548776 0.78 CYP2A6 (0.52) CYP2A6CYP2E1CYP2B6KCNH2CYP11B2
SCHEMBL26246 0.78 MMP3 (0.74) CYP2A6MMP3ALDH1A1KIF11CYP11B2
SCHEMBL396846 0.78 MMP3 (0.74) CYP2A6MMP3ALDH1A1KIF11CYP11B2
SCHEMBL13063633 0.78 MMP3 (0.74) CYP2A6MMP3ALDH1A1KIF11CYP11B2
Water SCHEMBL11055485 0.78 MMP3 (0.74) CYP2A6MMP3ALDH1A1KIF11CYP11B2
SCHEMBL4277917 0.77 PARP15 (0.44) MMP3ALDH1A1KIF11KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114196013-B Thienyl carbon-nitrogen conjugated polymer and preparation method and application thereof 浙江工业大学 2023-12-05 CN claimed
CN-114196013-A Thienyl carbon-nitrogen conjugated polymer and preparation method and application thereof 浙江工业大学 2022-03-18 CN claimed
CN-114196013-B Thienyl carbon-nitrogen conjugated polymer and preparation method and application thereof 浙江工业大学 2023-12-05 CN disclosed
CN-114196013-B Thienyl carbon-nitrogen conjugated polymer and preparation method and application thereof 浙江工业大学 2023-12-05 CN disclosed
CN-114196013-A Thienyl carbon-nitrogen conjugated polymer and preparation method and application thereof 浙江工业大学 2022-03-18 CN disclosed
CN-114196013-A Thienyl carbon-nitrogen conjugated polymer and preparation method and application thereof 浙江工业大学 2022-03-18 CN disclosed
CN-107573386-A Complex of iridium containing thieno [2,3 d] pyrimidine group and the application in electroluminescent device 武汉大学 2018-01-12 CN disclosed
US-20060008703-A1 Polymer materials for use in an electrode IM&T RESEARCH, INC. 2006-01-12 US disclosed
US-20030044680-A1 Polymers contain units having at least one cyclopentanone structure condensed with at least two aromatic rings. e.g., units of 9-fluorenone, cyclopenta(def)fluorene-4,8-dione, and benzo(b)fluoren-11-one. IM&T RESEARCH, INC. 2003-03-06 US disclosed