Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698626 | 0.91 | GAA (0.49) | AKR1C2PTGDRPTGDR2PTPN5MAPT | |
| SCHEMBL7693001 | 0.90 | AKR1C2 (0.49) | AKR1C2PTGDRPTGDR2PTPN5MAPT | |
| SCHEMBL7694013 | 0.89 | AKR1C2 (0.46) | AKR1C2PTGDRPTGDR2PTPN5MAPT | |
| SCHEMBL7699710 | 0.89 | AKR1C2 (0.46) | AKR1C2PTGDRPTGDR2PTPN5MAPT | |
| SCHEMBL7698767 | 0.87 | AKR1C2 (0.46) | AKR1C2PTGDRPTGDR2PTPN5MAPT | |
| SCHEMBL8891252 | 0.87 | HTT (0.43) | PTGDRPTGDR2PTPN5MAPTGAA | |
| SCHEMBL8672196 | 0.87 | PTGDR (0.39) | AKR1C2PTGDRPTGDR2PTPN5MAPT | |
| SCHEMBL7692673 | 0.87 | AKR1C2 (0.45) | AKR1C2PTGDRPTGDR2PTPN5MAPT | |
| SCHEMBL5810898 | 0.87 | PTGS1 (0.48) | AKR1C2PTGDRPTGDR2PTPN5MAPT | |
| SCHEMBL8671632 | 0.84 | PTGS1 (0.40) | PTGDRPTGDR2PTPN5MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968371-A2 | MODULATION OF CELLULAR DNA REPAIR ACTIVITY TO INTERCEPT MALIGNANCY | The Board of Trustees of the Leland Stanford Junior University (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014164730-A2 | MODULATION OF CELLULAR DNA REPAIR ACTIVITY TO INTERCEPT MALIGNANCY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-10-09 | — | — | WO | claimed |
| EP-1617828-A2 | NANO-SIZED VEHICLES TRANSPORTING A THERAPEUTIC AGENT AND AT LEAST ONE DRUG RESISTANCE MODULATOR FOR THE TREATMENT OF MULTI DRUG RESISTANCE | Celator Pharmaceuticals, Inc. (US) | 2006-01-25 | — | — | EP | disclosed |
| WO-2004087094-A2 | NANO-SIZED VEHICLES TRANSPORTING A THERAPEUTIC AGENT AND AT LEAST ONE DRUG RESISTANCE MODULATOR FOR THE TREATMENT OF MULTI DRUG RESISTANCE | CELATOR PHARMACEUTICALS, INC. (US) | 2004-10-14 | — | — | WO | disclosed |
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | disclosed |