Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013487 | 0.87 | AKR1C2 (0.46) | PTPN5GAAALDH1A1PTGS1PTGS2 | |
| SCHEMBL8668653 | 0.83 | HTT (0.40) | HTTPTPN5ALDH1A1PTGDR2ALOX5 | |
| SCHEMBL5809994 | 0.81 | L3MBTL1 (0.44) | HTTALDH1A1PTGDRPTGDR2MET | |
| SCHEMBL5809697 | 0.80 | PTGS1 (0.46) | PTPN5ALDH1A1PTGS1PTGS2POLB | |
| SCHEMBL8671632 | 0.80 | PTGS1 (0.40) | HTTPTPN5ALDH1A1PTGS1PTGS2 | |
| SCHEMBL8672196 | 0.79 | PTGDR (0.39) | PTPN5PTGS1PTGS2PTGDRPTGDR2 | |
| SCHEMBL8668568 | 0.79 | PTGS1 (0.42) | PTPN5ALDH1A1PTGS1PTGS2PTGDR | |
| SCHEMBL8675619 | 0.78 | PTGS1 (0.39) | PTPN5ALDH1A1PTGS1PTGS2PTGDR | |
| SCHEMBL6589367 | 0.78 | PTGS1 (0.40) | PTPN5ALDH1A1PTGS1PTGS2PTGDR | |
| SCHEMBL7698626 | 0.78 | GAA (0.49) | PTPN5GAAALDH1A1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | disclosed |