Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013487 | 0.87 | AKR1C2 (0.46) | PTGDRPTGDR2PTPN5PTGS1PTGS2 | |
| SCHEMBL8891252 | 0.79 | HTT (0.43) | PTGDRPTGDR2PTPN5PTGS1PTGS2 | |
| SCHEMBL7698626 | 0.78 | GAA (0.49) | PTGDRPTGDR2PTPN5PTGS1PTGS2 | |
| SCHEMBL7698767 | 0.77 | AKR1C2 (0.46) | PTGDRPTGDR2PTPN5AKR1C2LMNA | |
| SCHEMBL7693001 | 0.77 | AKR1C2 (0.49) | PTGDRPTGDR2PTPN5AKR1C2SLC2A1 | |
| SCHEMBL7694013 | 0.77 | AKR1C2 (0.46) | PTGDRPTGDR2PTPN5PTGS1PTGS2 | |
| SCHEMBL7699710 | 0.77 | AKR1C2 (0.46) | PTGDRPTGDR2PTPN5PTGS1PTGS2 | |
| SCHEMBL8671632 | 0.76 | PTGS1 (0.40) | PTGDRPTGDR2PTPN5PTGS1PTGS2 | |
| SCHEMBL8642541 | 0.76 | PTPN5 (0.37) | PTGDRPTGDR2PTPN5PTGS1PTGS2 | |
| SCHEMBL8646867 | 0.76 | PTPN5 (0.38) | PTGDRPTGDR2PTPN5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750558-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |