SCHEMBL6013660

SCHEMBL6013660

C=CC(=O)OCCOCC(O)CN1C(=O)N(CC(O)COCCOC(=O)C=C)C(C)(C)C1=O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.40
ALDH1A1 P00352 4/20 0.40
TP53 P04637 2/20 0.40
HIF1A Q16665 2/20 0.40
HSD17B10 Q99714 1/20 0.40
RAB9A P51151 2/20 0.40
THRB P10828 2/20 0.36
MAPK1 P28482 2/20 0.35
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
MMP2 P08253 2/20 0.32
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
CYP3A4 P08684 1/20 0.31
MMP3 P08254 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11385326 0.89 RAB9A (0.43) TSHRALDH1A1RAB9AMAPK1SMN1; SMN2
SCHEMBL11097467 0.87 ALDH1A1 (0.32) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9014246 0.85 RAB9A (0.37) RAB9AMAPK1
SCHEMBL11127283 0.85 RAB9A (0.42) TSHRALDH1A1HSD17B10RAB9AMAPK1
SCHEMBL9284350 0.84 RAB9A (0.40) TSHRALDH1A1RAB9ATHRBMAPK1
SCHEMBL11638492 0.83 RAB9A (0.51) TSHRALDH1A1HSD17B10RAB9AMAPK1
SCHEMBL8520596 0.81 TSHR (0.42) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL11637353 0.81 RAB9A (0.37) TSHRRAB9ALMNAMMP2MMP3
SCHEMBL9014242 0.81 RAB9A (0.37) TSHRRAB9A
SCHEMBL13142224 0.79 RAB9A (0.33) ALDH1A1TP53HIF1ARAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0079372-B1 PRIMED INORGANIC SUBSTRATES OVERCOATED WITH CURABLE PROTECTIVE COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-10-08 EP claimed
US-4356233-A SILANE AND METAL ESTER IN ACETIC MEDIUM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-10-26 US claimed
EP-1232875-B1 Tissue paper used for heat-sensitive stencil sheet, heat-sensitive stencil sheet, and method of making the same RICOH KK (JP) 2006-08-23 EP disclosed
US-6946049-B2 Tissue paper used for heat-sensitive stencil sheet, heat-sensitive stencil sheet, and method of making the same RICOH COMPANY, LTD. (JP) 2005-09-20 US disclosed
EP-1232876-B1 Heat-sensitive stencil sheet and method of making the same RICOH KK (JP) 2005-05-04 EP disclosed
US-6866924-B2 Tissue paper used for heat-sensitive stencil sheet, heat-sensitive stencil sheet, and method of making the same RICOH COMPANY, LTD. (JP) 2005-03-15 US disclosed
US-20030150576-A1 Tissue paper used for heat-sensitive stencil sheet, heat-sensitive stencil sheet, and method of making the same RICOH COMPANY, LTD. (JP) 2003-08-14 US disclosed
US-20030070753-A1 A lamination comprising a porous resin layer coated on one side of thermoplastic resin film, and a porous fiber layer bonded by an adhesive to the surface of the porous resin layer; bonding strength, colorfastness RICOH COMPANY, LTD. 2003-04-17 US disclosed
US-20030031855-A1 Tissue paper used for heat-sensitive stencil sheet, heat-sensitive stencil sheet, and method of making the same RICOH COMPANY, LTD. AND TOHOKU RICOH COMPANY, LTD. 2003-02-13 US disclosed
EP-1232876-A2 Heat-sensitive stencil sheet and method of making the same Ricoh Company (JP) 2002-08-21 EP disclosed
EP-1232875-A1 Tissue paper used for heat-sensitive stencil sheet, heat-sensitive stencil sheet, and method of making the same Ricoh Company (JP) 2002-08-21 EP disclosed
US-4396650-A POLYSILOXANES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-08-02 US disclosed
EP-0079372-A1 PRIMED INORGANIC SUBSTRATES OVERCOATED WITH CURABLE PROTECTIVE COMPOSITIONS. MINNESOTA MINING & MFG (US) 1983-05-25 EP disclosed
WO-1982004015-A1 PRIMED INORGANIC SUBSTRATES OVERCOATED WITH CURABLE PROTECTIVE COMPOSITIONS MINNESOTA MINING & MFG (US) 1982-11-25 WO disclosed
US-4356233-A SILANE AND METAL ESTER IN ACETIC MEDIUM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-10-26 US disclosed
EP-0030969-A4 POLY(ETHYLENICALLY UNSATURATED ALKOXY)HETEROCYCLIC COMPOUNDS AND CROSSLINKED POLYMERIC COATINGS. MINNESOTA MINING & MFG (US) 1981-10-27 EP disclosed
EP-0030969-A1 POLY(ETHYLENICALLY UNSATURATED ALKOXY)HETEROCYCLIC COMPOUNDS AND CROSSLINKED POLYMERIC COATINGS. MINNESOTA MINING & MFG (US) 1981-07-01 EP disclosed
US-4262072-A ABRASION RESISTANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-04-14 US disclosed
US-4249011-A CURING AGENTS FOR ADDITION PHOTOPOLYMERIZATION MINNESOTA MINING AND MANUFACTURING COMPANY 1981-02-03 US disclosed
WO-1981000011-A1 POLY(ETHYLENICALLY UNSATURATED ALKOXY)HETEROCYCLIC COMPOUNDS AND CROSSLINKED POLYMERIC COATINGS MINNESOTA MINING & MFG (US) 1981-01-08 WO disclosed