Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SHBG | P04278 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.59 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11480876 | 1.00 | HIF1A (0.59) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL9459018 | 1.00 | HIF1A (0.59) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL30496663 | 1.00 | HIF1A (0.59) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL3671489 | 1.00 | HIF1A (0.59) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL3321767 | 0.88 | SMN1; SMN2 (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11154815 | 0.87 | HIF1A (0.55) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL24722640 | 0.86 | HIF1A (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL10627809 | 0.86 | HIF1A (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL10627802 | 0.86 | HIF1A (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL10627817 | 0.86 | HIF1A (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627030-A1 | NITROGEN REJECTION FROM CONDENSED NATURAL GAS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2006-02-22 | — | — | EP | claimed |
| WO-2004104143-A1 | NITROGEN REJECTION FROM CONDENSED NATURAL GAS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-12-02 | — | — | WO | claimed |
| WO-2004103376-A2 | SKIN TREATMENTS | UNILEVER PLC (GB) | 2004-12-02 | — | — | WO | claimed |
| EP-0350488-B1 | 1,2-DEHYDROGENATION OF STEROIDAL 21-ESTERS WITH A. SIMPLEX | THE UPJOHN COMPANY (US) | 1993-09-08 | — | — | EP | claimed |
| US-4749649-A | Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen | THE UPJOHN COMPANY (US) | 1988-06-07 | — | — | US | claimed |
| EP-0127294-B1 | STEROID DEHYDROGENATION | THE UPJOHN COMPANY (US) | 1986-12-17 | — | — | EP | claimed |
| EP-0350488-B1 | 1,2-DEHYDROGENATION OF STEROIDAL 21-ESTERS WITH A. SIMPLEX | THE UPJOHN COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5225335-A | Enzymatic dehydrogenation | THE UPJOHN COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-4749649-A | Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen | THE UPJOHN COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
| US-4704358-A | Δ1 -dehydrogenation with heat or air-dried B. cyclooxidans | THE UPJOHN COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
| EP-0127294-A1 | Steroid dehydrogenation | THE UPJOHN COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
| US-4189430-A | Epoxide process | THE UPJOHN COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0007766-A2 | Epoxypregnadienes, hydroxypregnatrienes, process for their preparation and process for their conversion to precursors of useful anti-inflammatory agents | THE UPJOHN COMPANY (US) | 1980-02-06 | — | — | EP | disclosed |