Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SHBG | P04278 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.59 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013906 | 1.00 | HIF1A (0.59) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11480876 | 1.00 | HIF1A (0.59) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL9459018 | 1.00 | HIF1A (0.59) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL30496663 | 1.00 | HIF1A (0.59) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL3321767 | 0.88 | SMN1; SMN2 (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11154815 | 0.87 | HIF1A (0.55) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL24722640 | 0.86 | HIF1A (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL10627809 | 0.86 | HIF1A (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL10627802 | 0.86 | HIF1A (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL10627817 | 0.86 | HIF1A (0.60) | HIF1ANR3C2SMN1; SMN2SERPINA6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432399-A1 | ENHANCING EPIDERMAL BARRIER DEVELOPMENT IN SKIN | UNILEVER PLC (GB) | 2004-06-30 | — | — | EP | claimed |
| US-20030124159-A1 | Enhancing epidermal barrier development in skin | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC | 2003-07-03 | — | — | US | claimed |
| WO-2003030857-A1 | ENHANCING EPIDERMAL BARRIER DEVELOPMENT IN SKIN | UNILEVER PLC (GB) | 2003-04-17 | — | — | WO | claimed |
| EP-0350488-B1 | 1,2-DEHYDROGENATION OF STEROIDAL 21-ESTERS WITH A. SIMPLEX | THE UPJOHN COMPANY (US) | 1993-09-08 | — | — | EP | claimed |
| US-4749649-A | Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen | THE UPJOHN COMPANY (US) | 1988-06-07 | — | — | US | claimed |
| EP-0127294-B1 | STEROID DEHYDROGENATION | THE UPJOHN COMPANY (US) | 1986-12-17 | — | — | EP | claimed |
| EP-0127294-A1 | Steroid dehydrogenation | THE UPJOHN COMPANY (US) | 1984-12-05 | — | — | EP | claimed |
| US-10456344-B2 | Hair composition | CONOPCO, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| US-10406091-B2 | Skin anti-ageing composition | CONOPCO, INC. (US) | 2019-09-10 | — | — | US | disclosed |
| EP-2788088-B1 | SKIN ANTI-AGEING COMPOSITION | UNILEVER PLC (GB) | 2019-06-19 | — | — | EP | disclosed |
| US-20170360673-A1 | HAIR COMPOSITION | CONOPCO, INC., D/B/A UNILEVER (US) | 2017-12-21 | — | — | US | disclosed |
| EP-2788088-A1 | SKIN ANTI-AGEING COMPOSITION | Unilever Plc. (GB) | 2014-10-15 | — | — | EP | disclosed |
| US-20140295010-A1 | SKIN ANTI-AGEING COMPOSITION | CONOPCO, INC. D/B/A UNILEVER (US) | 2014-10-02 | — | — | US | disclosed |
| WO-2003030857-A1 | ENHANCING EPIDERMAL BARRIER DEVELOPMENT IN SKIN | UNILEVER PLC (GB) | 2003-04-17 | — | — | WO | disclosed |
| EP-0350488-B1 | 1,2-DEHYDROGENATION OF STEROIDAL 21-ESTERS WITH A. SIMPLEX | THE UPJOHN COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5225335-A | Enzymatic dehydrogenation | THE UPJOHN COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-4749649-A | Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen | THE UPJOHN COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
| US-4704358-A | Δ1 -dehydrogenation with heat or air-dried B. cyclooxidans | THE UPJOHN COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
| EP-0127294-A1 | Steroid dehydrogenation | THE UPJOHN COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
| US-4189430-A | Epoxide process | THE UPJOHN COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030124159-A1 | Enhancing epidermal barrier development in skin | NR1H2, NR1H3, RXRB | HIF1A 538/4885NR3C2 471/4885SMN1; SMN2 4529/4885 |
| US-10456344-B2 | Hair composition | GLS2, GLS, LHCGR | HIF1A 2417/4885NR3C2 69/4885SMN1; SMN2 4563/4885 |
| US-20170360673-A1 | HAIR COMPOSITION | GLS2, GLS, CYP17A1 | HIF1A 2563/4885NR3C2 79/4885SMN1; SMN2 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.