Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545981 | 0.78 | MEN1 (0.61) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL5054519 | 0.75 | SMN1; SMN2 (0.41) | MEN1ALDH1A1KMT2ASMN1; SMN2PDE4A | |
| SCHEMBL14820062 | 0.71 | ALDH1A1 (0.49) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL17582663 | 0.70 | YTHDF2 (0.43) | MEN1ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1945404 | 0.68 | ALDH1A1 (1.00) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL14805622 | 0.68 | ALDH1A1 (0.46) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL5906738 | 0.67 | KMT2A (0.47) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL21667364 | 0.65 | SMN1; SMN2 (0.46) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL4043882 | 0.65 | ALDH1A1 (0.66) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL4041385 | 0.65 | ALDH1A1 (0.65) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685132-A1 | A sb 2B /sb ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005051951-A1 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2005-06-09 | — | — | WO | disclosed |