Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31620950 | 0.92 | ACHE (0.52) | TDP1HSD17B10NPC1RAB9AALDH1A1 | |
| SCHEMBL28191136 | 0.92 | ACHE (0.52) | TDP1HSD17B10NPC1RAB9AALDH1A1 | |
| SCHEMBL260855 | 0.90 | ACHE (0.56) | TDP1HSD17B10CYP3A4NPC1RAB9A | |
| SCHEMBL29437718 | 0.90 | ACHE (0.56) | TDP1HSD17B10CYP3A4NPC1RAB9A | |
| SCHEMBL22898969 | 0.89 | TAAR1 (0.54) | TDP1HSD17B10CYP3A4TAAR1NPC1 | |
| SCHEMBL27771826 | 0.89 | ADORA2A (0.44) | TDP1HSD17B10CYP3A4TAAR1NPC1 | |
| SCHEMBL5851572 | 0.88 | ACHE (0.52) | TDP1HSD17B10NPC1RAB9AALDH1A1 | |
| SCHEMBL25301803 | 0.88 | HSD17B10 (0.61) | TDP1HSD17B10CYP3A4TAAR1NPC1 | |
| SCHEMBL650894 | 0.88 | CYP3A4 (0.61) | TDP1HSD17B10CYP3A4TAAR1NPC1 | |
| SCHEMBL21582646 | 0.88 | HSD17B10 (0.61) | TDP1HSD17B10CYP3A4TAAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112392-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge for image forming apparatus using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2006-09-26 | — | — | US | disclosed |
| US-20040170911-A1 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge for image forming apparatus using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2004-09-02 | — | — | US | disclosed |