Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYB | P10242 | 5/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.55 |
| ▸ | TUBB | P07437 | 3/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4531879 | 0.88 | MYB (0.65) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5048290 | 0.88 | HTT (0.70) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6014321 | 0.82 | MEN1 (0.43) | MYBHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6014204 | 0.79 | MYB (0.89) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4328410 | 0.76 | TUBB4A (0.75) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15363961 | 0.74 | HTT (0.86) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4535837 | 0.74 | TUBB4A (0.69) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1751160 | 0.74 | SMN1; SMN2 (0.85) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4322223 | 0.74 | TUBB4A (0.78) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4319503 | 0.73 | TUBB4A (0.70) | MYBTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062901-A2 | CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) | 2012-05-18 | — | — | WO | disclosed |