⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27489680 | 0.98 | — | — | |
| SCHEMBL19708774 | 0.78 | — | — | |
| SCHEMBL27626375 | 0.74 | — | — | |
| SCHEMBL28005483 | 0.74 | — | — | |
| SCHEMBL27464507 | 0.74 | HTR2C (0.30) | — | |
| SCHEMBL10961104 | 0.74 | ADRB1 (0.31) | — | |
| SCHEMBL15654190 | 0.74 | SIGMAR1 (0.31) | — | |
| Water SCHEMBL27462314 | 0.72 | — | — | |
| SCHEMBL5919636 | 0.71 | — | — | |
| SCHEMBL28528955 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021397-A4 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS INC (US) | 2000-10-04 | — | — | EP | claimed |
| EP-1021397-A1 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS INC. (US) | 2000-07-26 | — | — | EP | claimed |
| WO-1998039287-A1 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS, INC. (US) | 1998-09-11 | — | — | WO | claimed |
| EP-1633712-B1 | SIX MEMBERED AMINO-AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | CHEN GUOQING PAUL (US) | 2014-06-25 | — | — | EP | disclosed |
| CN-100543032-C | Streptogramin derivatives, preparation method and compositions containing them | AVETIS PHARMA S A (FR) | 2009-09-23 | — | — | CN | disclosed |
| CN-1961878-A | Streptogramin derivatives, their preparation and compositions containing them | AVENTIS PHARMA SA (FR) | 2007-05-16 | — | — | CN | disclosed |
| US-7129252-B2 | Six membered amino-amide derivatives an angiogenisis inhibitors | HLB CO., LTD. (KR) | 2006-10-31 | — | — | US | disclosed |
| EP-1633712-A2 | SIX MEMBERED AMINO-AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | Chen, Guoqing Paul (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2005000232-A2 | SIX MEMBERED AMINO-AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | CHEN GUOQING PAUL (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040259916-A1 | Six membered amino-amide derivatives an angiogenisis inhibitors | HLB CO., LTD. (KR) | 2004-12-23 | — | — | US | disclosed |
| CN-1136191-C | Carboxy substituted carboxamide derivatives as tachykinin receptor antagonists | ������ҩ������˾ | 2004-01-28 | — | — | CN | disclosed |
| CN-1358194-A | Streptogramin derivatives, preparation method and compositions containing them | AVETIS PHARMA S A (FR) | 2002-07-10 | — | — | CN | disclosed |
| CN-1301253-A | Carboxy substituted carboxamide derivatives as tachykinin receptor antagonists | AVENTIS PHARMACEUTICAL INC (US) | 2001-06-27 | — | — | CN | disclosed |
| EP-1021397-A4 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS INC (US) | 2000-10-04 | — | — | EP | disclosed |
| EP-1021397-A1 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998039287-A1 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS, INC. (US) | 1998-09-11 | — | — | WO | disclosed |