SCHEMBL601473

SCHEMBL601473

Nc1ccc(-c2nnc(-c3ccc(N)cc3)o2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 13/20 1.00
RAB9A P51151 13/20 1.00
MEN1 O00255 3/20 0.83
KMT2A Q03164 3/20 0.83
SMN1; SMN2 Q16637 7/20 0.79
KDM4E B2RXH2 7/20 0.79
ALDH1A1 P00352 6/20 0.79
HPGD P15428 6/20 0.79
HSD17B10 Q99714 3/20 0.79
MAPT P10636 3/20 0.79
GLA P06280 2/20 0.79
ALOX15 P16050 1/20 0.79
TP53 P04637 4/20 0.70
NFKB1 P19838 2/20 0.70
NFKB2 Q00653 2/20 0.70
RELA Q04206 2/20 0.70
POLB P06746 2/20 0.63
MECP2 P51608 1/20 0.55
PKM P14618 1/20 0.54
NOTUM Q6P988 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8650657 0.91 RAB9A (1.00) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL3173832 0.89 NPC1 (0.79) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL28671885 0.89 NPC1 (0.79) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL4876686 0.89 NPC1 (0.79) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL10947541 0.87 NPC1 (0.76) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL16521527 0.87 NPC1 (0.76) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL2159951 0.86 NPC1 (0.74) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL221481 0.84 NPC1 (0.72) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL7724942 0.84 RAB9A (0.72) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL2837217 0.84 NPC1 (0.72) NPC1RAB9AMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118684849-A Covalent organic framework solid-state fluorescence sensor, preparation method thereof and application for measuring water content in organic solvent 安康学院 2024-09-24 CN claimed
CN-113683085-B Preparation method of aminated graphene oxide 常州恒利宝纳米新材料科技有限公司 2023-11-21 CN claimed
CN-113185802-B Melamine-formaldehyde resin coated vanadium dioxide photothermal response composite nano-particle and preparation method thereof 济南大学 2022-07-22 CN claimed
US-8885135-B2 Nanostructure-film LCD devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-11-11 US claimed
US-20120308771-A1 NANOSTRUCTURE FILMS DRAZAIC PAUL (US) 2012-12-06 US claimed
JP-2011527809-A 2011-11-04 JP claimed
US-8017175-B2 Manufacturing multilayer conjugate polymer optoelectronics device by using buffer layer NATIONAL CHIAO TUNG UNIVERSITY (TW) 2011-09-13 US claimed
US-7960080-B2 Oxadiazole containing photoconductors XEROX CORPORATION (US) 2011-06-14 US claimed
WO-2009152146-A1 IMPROVED CNT/TOPCOAT PROCESSES FOR MAKING A TRANSPLANT CONDUCTOR UNIDYM, INC. (US) 2009-12-17 WO claimed
US-20090246664-A1 OXADIAZOLE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US claimed
US-20040142183-A1 Anisotropic film manufacturing INSOLVENCY SERVICES GROUP, INC. 2004-07-22 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
EP-0577245-B1 Photogenerating azo pigments XEROX CORP (US) 1998-12-02 EP claimed
US-5281503-A Multilayer element with disazo pigments and charge generating layer XEROX CORPORATION (US) 1994-01-25 US claimed
EP-0577245-A1 Photogenerating azo pigments XEROX CORPORATION (US) 1994-01-05 EP claimed
US-4526835-A Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure HITACHI, LTD. (JP) 1985-07-02 US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US claimed
US-4393188-A PRINTED CIRCUITS HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-07-12 US claimed
US-4283522-A BY HEATING WITH A DIAMINE HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-08-11 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed