Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.72 |
| ▸ | NPC1 | O15118 | 12/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | MECP2 | P51608 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601473 | 0.84 | NPC1 (1.00) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL28353634 | 0.79 | NPC1 (0.64) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL9364714 | 0.79 | ACHE (0.47) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19558149 | 0.79 | NPC1 (0.72) | RAB9ANPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL28628120 | 0.79 | DGAT1 (0.60) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL23390701 | 0.79 | NPC1 (0.43) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL988353 | 0.79 | NPC1 (0.62) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL9058872 | 0.79 | NPC1 (0.60) | RAB9ANPC1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL27844547 | 0.79 | HRH3 (0.46) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL406885 | 0.78 | NPC1 (0.70) | RAB9ANPC1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025078867-A1 | WATER MONITORING SENSOR, METHODS OF PRODUCTION AND USES | INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY (INL) (PT) | 2025-04-17 | — | — | WO | claimed |
| EP-3624791-B1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | UNIV CITY NEW YORK RES FOUND (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025078867-A1 | WATER MONITORING SENSOR, METHODS OF PRODUCTION AND USES | INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY (INL) (PT) | 2025-04-17 | — | — | WO | disclosed |
| US-11000604-B2 | Reagent for site-selective bioconjugation of proteins or antibodies | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200397928-A1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2020-12-24 | — | — | US | disclosed |
| US-10752624-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2020-08-25 | — | — | US | disclosed |
| EP-3624791-A1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | Research Foundation Of The City University Of New York (US) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018213537-A1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2018-11-22 | — | — | WO | disclosed |
| US-20180305356-A1 | NOVEL KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2018-10-25 | — | — | US | disclosed |
| US-10000482-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| US-20120252777-A1 | THIAZOLOPYRIMIDINE COMPOUNDS | HOFFMANN-LA ROCHE INC. | 2012-10-04 | — | — | US | disclosed |
| US-20120252777-A1 | THIAZOLOPYRIMIDINE COMPOUNDS | HOFFMANN-LA ROCHE INC. | 2012-10-04 | — | — | US | disclosed |
| WO-2012130780-A1 | THIAZOLOPYRIMIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012130780-A1 | THIAZOLOPYRIMIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-10-04 | — | — | WO | disclosed |
| US-20120252777-A1 | THIAZOLOPYRIMIDINE COMPOUNDS | HOFFMANN-LA ROCHE INC. | 2012-10-04 | — | — | US | disclosed |
| US-20120168681-A1 | Surface Modified Metal Nano-Particle and Use Thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2012-07-05 | — | — | US | disclosed |
| US-20120053214-A1 | THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF | HAN MEI (CN) | 2012-03-01 | — | — | US | disclosed |
| US-20120053214-A1 | THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF | HAN MEI (CN) | 2012-03-01 | — | — | US | disclosed |
| US-6420367-B1 | RAS GENE | SHIONOGO & CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1097933-A1 | PYRIMIDINE DERIVATIVES EXHIBITING ANTITUMOR ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200397928-A1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | MRPL21, TFRC, ARGLU1 | RAB9A 2630/4885NPC1 4336/4885MEN1 50/4885 |
| US-20180305356-A1 | NOVEL KINASE INHIBITORS | LRRK2, MYLK2, MYLK | RAB9A 872/4885NPC1 4398/4885MEN1 544/4885 |
| US-11000604-B2 | Reagent for site-selective bioconjugation of proteins or antibodies | MRPL21, TFRC, ARGLU1 | RAB9A 2630/4885NPC1 4336/4885MEN1 50/4885 |
| US-20120252777-A1 | THIAZOLOPYRIMIDINE COMPOUNDS | SYK, BTK, ZAP70 | RAB9A 3913/4885NPC1 4274/4885MEN1 3729/4885 |
| US-10000482-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | RAB9A 860/4885NPC1 4434/4885MEN1 636/4885 |
| US-10752624-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | RAB9A 860/4885NPC1 4434/4885MEN1 636/4885 |
| US-20120053214-A1 | THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF | MKI67, KIT, PCNA | RAB9A 2617/4885NPC1 2926/4885MEN1 3797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.