Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | UBE2M | P61081 | 5/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949665 | 0.90 | UBE2M (0.42) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL949892 | 0.87 | OPRM1 (0.46) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL3448469 | 0.83 | OPRM1 (0.48) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL949666 | 0.81 | OPRM1 (0.37) | OPRM1CHRM2CHRM3SIGMAR1DRD2 | |
| SCHEMBL948539 | 0.79 | OPRM1 (0.41) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL948385 | 0.74 | OPRM1 (0.42) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL6220319 | 0.72 | DCUN1D1 (0.51) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL6219028 | 0.71 | DCUN1D1 (0.52) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL948540 | 0.70 | OPRM1 (0.37) | OPRM1CHRM2CHRM3LMNASIGMAR1 | |
| SCHEMBL6218807 | 0.70 | UBE2M (0.49) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
| EP-1564213-A1 | IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |