SCHEMBL6015039

SCHEMBL6015039

CC(C)(C)[C@@H](NC(=O)O)C(=O)N1CCC(N2CCCCC2=O)CC1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 3/20 0.47
F10 P00742 3/20 0.42
CCR1 P32246 2/20 0.42
KDM5A P29375 1/20 0.38
ENPP2 Q13822 2/20 0.38
CTSS P25774 1/20 0.36
MCHR1 Q99705 1/20 0.35
SPR P35270 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015105 0.96 VNN1 (0.46) VNN1F10CCR1KDM5AENPP2
SCHEMBL3448786 0.86 VNN1 (0.43) VNN1F10CCR1KDM5AENPP2
SCHEMBL6015018 0.81 CCR1 (0.41) VNN1CCR1
SCHEMBL6015002 0.81 F10 (0.43) VNN1F10CCR1CTSSMCHR1
SCHEMBL3448904 0.80 CCR1 (0.48) VNN1F10CCR1MCHR1CYP3A4
SCHEMBL16602550 0.79 CCR1 (0.41) CCR1
SCHEMBL3450076 0.79 VNN1 (0.42) VNN1F10CCR1KDM5AENPP2
SCHEMBL6015101 0.79 CCR1 (0.42) F10CCR1ENPP2MCHR1CYP3A4
SCHEMBL6014992 0.79 CCR1 (0.42) VNN1CCR1MCHR1CYP3A4CYP2C19
SCHEMBL19001333 0.77 KDM5A (0.50) VNN1F10KDM5AENPP2SPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1695961-A1 UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2006-08-30 EP disclosed