Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 3/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015039 | 0.96 | VNN1 (0.47) | VNN1CCR1KDM5AF10SPR | |
| SCHEMBL3448786 | 0.90 | VNN1 (0.43) | VNN1CCR1KDM5AF10SPR | |
| SCHEMBL6015018 | 0.82 | CCR1 (0.41) | VNN1CCR1 | |
| SCHEMBL6015002 | 0.81 | F10 (0.43) | VNN1CCR1F10MCHR1 | |
| SCHEMBL19001333 | 0.81 | KDM5A (0.50) | VNN1KDM5AF10SPRENPP2 | |
| SCHEMBL6014992 | 0.80 | CCR1 (0.42) | VNN1CCR1MCHR1 | |
| SCHEMBL6015101 | 0.80 | CCR1 (0.42) | CCR1F10ENPP2MMP13MCHR1 | |
| SCHEMBL3450101 | 0.79 | CCR1 (0.48) | VNN1CCR1F10MCHR1RAB9A | |
| SCHEMBL3448782 | 0.78 | VNN1 (0.41) | VNN1CCR1KDM5AF10SPR | |
| SCHEMBL16602550 | 0.77 | CCR1 (0.41) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |