SCHEMBL6015040

SCHEMBL6015040

Cc1ncc2n1C(=O)N(N1CCN(C(=O)[C@H](NC(=O)O)C(C)C)CC1)C2

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F10 P00742 3/20 0.45
ABL1 P00519 1/20 0.36
BCR P11274 1/20 0.36
F2 P00734 1/20 0.35
CCR1 P32246 8/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 2/20 0.33
TSHR P16473 1/20 0.33
P2RY12 Q9H244 1/20 0.33
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3450741 0.90 F10 (0.44) F10F2CCR1LMNA
SCHEMBL6015054 0.86 F10 (0.44) F10F2CCR1
SCHEMBL13123310 0.84 F10 (0.41) F10ABL1BCRF2CCR1
SCHEMBL3451344 0.84 CCR1 (0.48) F10F2CCR1KCNH2
SCHEMBL14541411 0.82 F10 (0.41) F10F2CCR1LMNAKMT2A
SCHEMBL6015061 0.82 F10 (0.42) F10F2CCR1
SCHEMBL6015019 0.81 F10 (0.53) F10F2CCR1KMT2AKCNH2
SCHEMBL3448456 0.81 F10 (0.42) F10F2
SCHEMBL3449377 0.81 F10 (0.46) F10F2
SCHEMBL6015135 0.80 ALDH1A1 (0.46) F10KMT2AP2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1695961-A1 UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2006-08-30 EP disclosed