Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015097 | 0.93 | F10 (0.44) | ALDH1A1F10SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL3450519 | 0.88 | FPR2 (0.49) | ALDH1A1F10MMP1MMP3 | |
| SCHEMBL3448772 | 0.88 | FPR2 (0.49) | ALDH1A1F10MMP1MMP3 | |
| SCHEMBL3451037 | 0.83 | F10 (0.51) | ALDH1A1F10SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6015060 | 0.83 | F10 (0.51) | ALDH1A1F10SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6014981 | 0.83 | F10 (0.43) | ALDH1A1F10KDM4EHSD17B10KMT2A | |
| SCHEMBL3450361 | 0.82 | HRH2 (0.49) | F10KMT2A | |
| SCHEMBL3451297 | 0.82 | F10 (0.43) | ALDH1A1F10SMN1; SMN2HSD17B10 | |
| SCHEMBL6015040 | 0.80 | F10 (0.45) | F10KMT2AP2RY12 | |
| SCHEMBL3451657 | 0.80 | F10 (0.45) | ALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |