Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703309 | 0.90 | TAS1R3 (0.58) | TAS1R3TAS1R1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL702807 | 0.88 | TAS1R3 (0.74) | TAS1R3TAS1R1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL704790 | 0.85 | TAS1R3 (0.59) | TAS1R3TAS1R1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL10273835 | 0.83 | TAS1R3 (0.67) | TAS1R3TAS1R1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL702030 | 0.80 | TAS1R3 (0.64) | TAS1R3TAS1R1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL30645001 | 0.80 | TAS1R3 (0.64) | TAS1R3TAS1R1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL30064606 | 0.80 | TAS1R3 (0.64) | TAS1R3TAS1R1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL20656729 | 0.78 | TAS1R3 (0.62) | TAS1R3TAS1R1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL22206085 | 0.78 | TAS1R3 (0.64) | TAS1R3TAS1R1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL30557690 | 0.77 | TAS1R3 (0.64) | TAS1R3TAS1R1SMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |