SCHEMBL702030

SCHEMBL702030

COc1ccc(CNC(=O)C(=O)NCCc2ccccn2)c(OC)c1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 6/20 0.64
TAS1R1 Q7RTX1 6/20 0.64
KMT2A Q03164 2/20 0.57
MTNR1A P48039 1/20 0.54
MTNR1B P49286 1/20 0.54
RAB9A P51151 3/20 0.51
GAA P10253 2/20 0.51
NPC1 O15118 2/20 0.51
MAPT P10636 2/20 0.51
ALDH1A1 P00352 3/20 0.49
TSHR P16473 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MEN1 O00255 1/20 0.49
TP53 P04637 1/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30064606 1.00 TAS1R3 (0.64) TAS1R3TAS1R1KMT2AMTNR1AMTNR1B
SCHEMBL30645001 1.00 TAS1R3 (0.64) TAS1R3TAS1R1KMT2AMTNR1AMTNR1B
SCHEMBL704733 0.94 MTNR1A (0.60) TAS1R3TAS1R1KMT2AMTNR1AMTNR1B
SCHEMBL702807 0.93 TAS1R3 (0.74) TAS1R3TAS1R1KMT2AMTNR1AMTNR1B
SCHEMBL19494675 0.92 TAS1R3 (0.54) TAS1R3TAS1R1KMT2AMTNR1AMTNR1B
SCHEMBL701181 0.89 TAS1R3 (0.64) TAS1R3TAS1R1KMT2ARAB9ANPC1
SCHEMBL30557690 0.89 TAS1R3 (0.64) TAS1R3TAS1R1KMT2ARAB9ANPC1
SCHEMBL703309 0.89 TAS1R3 (0.58) TAS1R3TAS1R1KMT2AMTNR1AMTNR1B
SCHEMBL701814 0.88 TAS1R3 (0.77) TAS1R3TAS1R1KMT2AMTNR1AMTNR1B
SCHEMBL701633 0.86 TAS1R3 (0.64) TAS1R3TAS1R1KMT2AMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118175935-A Composition and food for enhancing spicy taste 味之素株式会社 2024-06-11 CN claimed
CN-116058486-A Spicy enhancer composition and food 味之素株式会社 2023-05-05 CN claimed
WO-2023074853-A1 COMPOSITION FOR ENHANCING SPICY FLAVOR AND FOOD AJINOMOTO CO., INC. (JP) 2023-05-04 WO claimed
CN-106901311-B Flavor-developing peptide and application 丰益(上海)生物技术研发中心有限公司 2021-09-14 CN claimed
CN-106749516-B Novel taste-presenting peptide, preparation method and application thereof 丰益(上海)生物技术研发中心有限公司 2021-09-07 CN claimed
EP-3431464-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2019-01-23 EP claimed
EP-3235811-B1 PROCESS OF PREPARING OXALAMIDES SENOMYX INC (US) 2018-07-25 EP claimed
EP-3235811-A1 PROCESS OF PREPARING OXALAMIDES Senomyx, Inc. (US) 2017-10-25 EP claimed
EP-2742983-B1 Method for isolating fragrance and flavour compounds SYMRISE AG (DE) 2017-08-23 EP claimed
US-9144248-B2 Cinnamamides as savory flavorings SYMRISE AG (DE) 2015-09-29 US claimed
US-20120308703-A1 Cinnamamides as savory flavorings SYMRISE AG (DE) 2012-12-06 US claimed
EP-2529632-A1 Cinnamic acid amides as spicy flavour agents Symrise AG (DE) 2012-12-05 EP claimed
US-8148536-B2 Comestible compositions comprising high potency savory flavorants, and processes for producing them SENOMYX, INC. (US) 2012-04-03 US claimed
US-8124121-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX, INC. (US) 2012-02-28 US claimed
US-20090280230-A1 COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM SENOMYX, INC. 2009-11-12 US claimed
US-20090111834-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX, INC. 2009-04-30 US claimed
US-7476399-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX INC. (US) 2009-01-13 US claimed
EP-1659881-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2006-05-31 EP claimed
WO-2005041684-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX INC. (US) 2005-05-12 WO claimed
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products FIRMENICH INCORPORATED 2005-04-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090280230-A1 COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM TAS1R1, TAS1R2, GRM1 TAS1R3 12/4885TAS1R1 1/4885KMT2A 1743/4885
US-20090111834-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF TAS1R2, TAS1R1, TAS2R30 TAS1R3 5/4885TAS1R1 2/4885KMT2A 1575/4885
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products TAS2R40, TAS2R4, TAS2R30 TAS1R3 17/4885TAS1R1 11/4885KMT2A 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.