Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.62 |
| ▸ | RAB9A | P51151 | 12/20 | 0.62 |
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778209 | 0.79 | RAB9A (0.88) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6015577 | 0.77 | NPC1 (1.00) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6015594 | 0.76 | MAPT (1.00) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6015579 | 0.75 | NPC1 (1.00) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21451444 | 0.73 | NPC1 (0.56) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14778249 | 0.70 | RAB9A (0.52) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23440049 | 0.70 | MAPT (0.79) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6015593 | 0.70 | DYRK1A (0.46) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5510570 | 0.68 | MAPT (0.62) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10533789 | 0.68 | NPC1 (0.66) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8784782-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8784782-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130071536-A1 | COMPOUNDS COMPRISING LINKED HETEROARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130071536-A1 | COMPOUNDS COMPRISING LINKED HETEROARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |