Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CBX7 | O95931 | 2/20 | 0.44 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.44 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068285 | 0.83 | KMT2A (0.43) | ALDH1A1MAPTPOLBGAATSHR | |
| SCHEMBL2067370 | 0.78 | POLB (0.46) | ALDH1A1MAPTPOLBIRAK4MEN1 | |
| SCHEMBL2067169 | 0.77 | SMN1; SMN2 (0.50) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6015702 | 0.77 | KMT2A (0.46) | ALDH1A1MAPTPOLBGAAKMT2A | |
| SCHEMBL3774050 | 0.71 | KDM4E (0.73) | KDM4EALDH1A1MAPTGAACBX7 | |
| SCHEMBL28269625 | 0.70 | IRAK4 (0.57) | CBX7CDYL2CDYLCDY1; CDY1BL3MBTL3 | |
| SCHEMBL16845725 | 0.70 | IRAK4 (0.63) | KDM4EALDH1A1MAPTG6PDHPGD | |
| SCHEMBL12452076 | 0.69 | MEN1 (0.56) | KDM4EALDH1A1CYP2D6CYP2C19NPSR1 | |
| SCHEMBL6016055 | 0.69 | CBX7 (0.55) | POLBGAATSHRCYP2D6CYP2C19 | |
| SCHEMBL20807374 | 0.68 | L3MBTL3 (0.53) | KDM4EALDH1A1CYP2D6CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |