Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GPR4 | P46093 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068285 | 0.87 | KMT2A (0.43) | KMT2APOLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2067370 | 0.84 | POLB (0.46) | KMT2APOLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2067169 | 0.83 | SMN1; SMN2 (0.50) | KMT2APOLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6015646 | 0.77 | KDM4E (0.47) | KMT2APOLBALDH1A1GAAMAPT | |
| SCHEMBL13102474 | 0.72 | POLB (0.50) | KMT2APOLBALDH1A1TPSAB1TPSD1 | |
| SCHEMBL13066495 | 0.68 | ALDH1A1 (0.54) | KMT2APOLBALDH1A1GAAPKM | |
| SCHEMBL13149530 | 0.67 | KMT2A (0.47) | KMT2APOLBALDH1A1TPSAB1TPSD1 | |
| SCHEMBL16416393 | 0.67 | ALDH1A1 (0.54) | KMT2APOLBALDH1A1TPSAB1TPSD1 | |
| SCHEMBL1901376 | 0.67 | KMT2A (0.50) | KMT2APOLBALDH1A1TPSAB1TPSD1 | |
| SCHEMBL15322932 | 0.67 | POLB (0.50) | KMT2APOLBALDH1A1TPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |