Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015911 | 0.99 | MEN1 (0.43) | MEN1MAPTKMT2ALTA4HTDP1 | |
| SCHEMBL6015820 | 0.99 | MEN1 (0.43) | MEN1MAPTKMT2ALTA4HTDP1 | |
| SCHEMBL7614022 | 0.73 | MKNK1 (0.38) | LTA4HHRH3 | |
| SCHEMBL6015805 | 0.72 | LTA4H (0.56) | LTA4HHRH3 | |
| SCHEMBL7647550 | 0.72 | MEN1 (0.38) | MEN1MAPTKMT2ALTA4HSIGMAR1 | |
| SCHEMBL6015878 | 0.71 | TSHR (0.51) | TDP1TSHRHRH3 | |
| SCHEMBL6016063 | 0.71 | LTA4H (0.55) | KMT2ALTA4HHRH3 | |
| SCHEMBL6015938 | 0.71 | TSHR (0.51) | TDP1TSHRHRH3 | |
| SCHEMBL6015872 | 0.71 | LTA4H (0.55) | KMT2ALTA4HHRH3 | |
| SCHEMBL6015916 | 0.69 | LTA4H (0.60) | LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |