Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015943 | 0.73 | CYP2D6 (0.42) | KDM4ETSHRALDH1A1CYP2C19 | |
| SCHEMBL24485546 | 0.71 | DNM1 (0.63) | DNM1P2RX4ALOX15KDM4ETSHR | |
| SCHEMBL12260313 | 0.70 | ALDH1A1 (0.50) | DNM1ALDH1A1 | |
| SCHEMBL1557707 | 0.70 | DNM1 (0.43) | DNM1P2RX4ALOX15KDM4ETSHR | |
| SCHEMBL1527147 | 0.69 | DNM1 (0.72) | DNM1ALOX15KDM4ETSHRHPGD | |
| SCHEMBL7159679 | 0.68 | MEN1 (0.67) | DNM1ALOX15KDM4ETSHRHPGD | |
| SCHEMBL8773743 | 0.68 | DNM1 (0.76) | DNM1ALOX15KDM4ETSHRHPGD | |
| SCHEMBL20710636 | 0.68 | DNM1 (0.59) | DNM1P2RX4ALOX15KDM4ETSHR | |
| SCHEMBL8082772 | 0.68 | DNM1 (0.59) | DNM1P2RX4ALOX15KDM4ETSHR | |
| SCHEMBL23899001 | 0.68 | DNM1 (0.82) | DNM1KDM4ETSHRHPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |