Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016054 | 0.82 | MEN1 (0.34) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL6015756 | 0.76 | KDM4C (0.42) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL6015722 | 0.75 | MEN1 (0.46) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL31091152 | 0.74 | KDM4C (0.46) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL1345450 | 0.73 | KDM4C (0.49) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL9512181 | 0.72 | KDM4C (0.44) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL12510434 | 0.72 | MEN1 (0.49) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL27162889 | 0.71 | KDM4C (0.43) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL17675580 | 0.71 | L3MBTL1 (0.45) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL12634793 | 0.71 | KDM4C (0.47) | KDM4CMEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |