Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13472650 | 0.75 | KDM4E (0.67) | GAASMN1; SMN2NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL7900662 | 0.73 | L3MBTL1 (0.64) | MAPTGAASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6398857 | 0.73 | L3MBTL1 (0.68) | MAPTGAASMN1; SMN2NAMPTNPC1 | |
| SCHEMBL13350354 | 0.72 | L3MBTL1 (0.62) | GAASMN1; SMN2NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL10663533 | 0.72 | L3MBTL1 (0.62) | GAASMN1; SMN2NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL10013653 | 0.72 | ALDH1A1 (0.63) | GAASMN1; SMN2NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL49130 | 0.72 | L3MBTL1 (0.66) | SMN1; SMN2NAMPTNPC1ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5656951 | 0.72 | L3MBTL1 (0.66) | SMN1; SMN2NAMPTNPC1ALDH1A1L3MBTL1 | |
| SCHEMBL10854541 | 0.71 | QPCT (0.65) | LMNAGAASMN1; SMN2NAMPTNPC1 | |
| SCHEMBL9659480 | 0.71 | GAA (0.68) | MAPTGAASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |