Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015618 | 0.89 | KMT2A (0.45) | POLBL3MBTL1GAATSHRHTT | |
| SCHEMBL6016081 | 0.81 | TSHR (0.52) | POLBL3MBTL1GAATSHRKMT2A | |
| SCHEMBL3258076 | 0.79 | LMNA (0.38) | POLBGAALMNAKDM4E | |
| SCHEMBL2067169 | 0.76 | SMN1; SMN2 (0.50) | POLBL3MBTL1GAATSHRLMNA | |
| SCHEMBL6015745 | 0.75 | KDM4E (0.46) | POLBLMNAHTTSMN1; SMN2RXFP1 | |
| SCHEMBL23929061 | 0.74 | SMN1; SMN2 (0.82) | POLBTSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL31052729 | 0.71 | GAA (0.57) | POLBL3MBTL1GAALMNAKMT2A | |
| SCHEMBL84933 | 0.70 | TSHR (0.59) | POLBTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL6015718 | 0.70 | MAPK1 (0.55) | POLBGAALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6015651 | 0.69 | KDM4E (0.49) | POLBKMT2ASMN1; SMN2RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |