Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164841 | 0.89 | TAS1R3 (0.56) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8403078 | 0.84 | TAS1R3 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL31047584 | 0.82 | HDAC1 (0.72) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL31047585 | 0.82 | HDAC1 (0.72) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL13229323 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL13261997 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL18284381 | 0.80 | TAS1R3 (0.56) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8546538 | 0.79 | KDM4E (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL27736532 | 0.79 | KDM4E (0.60) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL30201504 | 0.79 | ALDH1A1 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |