SCHEMBL6015964

SCHEMBL6015964

CC(C)OCCOc1ccc2[c]c[nH]c2c1CN(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015642 0.83
SCHEMBL6015721 0.80
SCHEMBL6015843 0.79 HPGD (0.37) HPGD
SCHEMBL6016062 0.77
SCHEMBL6015731 0.77 MAPT (0.44) HPGD
SCHEMBL6016054 0.74 MEN1 (0.34)
SCHEMBL6015772 0.71 HPGD (0.51) HPGD
SCHEMBL6015960 0.70 ALDH1A1 (0.43) HPGD
SCHEMBL6015940 0.68 PTGES (0.32)
SCHEMBL6015865 0.66 HPGD (0.38) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7049312-B1 Benzothiazinone and benzoxazinone compounds ABBOTT GMBH & CO. KG (DE) 2006-05-23 US claimed
EP-1181282-A2 BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-02-27 EP claimed
WO-2000075139-A2 BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2000-12-14 WO claimed
US-7049312-B1 Benzothiazinone and benzoxazinone compounds ABBOTT GMBH & CO. KG (DE) 2006-05-23 US disclosed