Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL5315297 | 0.82 | AHR (0.68) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL31345932 | 0.75 | PIK3CD (0.43) | MAPT | |
| Acridine SCHEMBL3045498 | 0.74 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL4972293 | 0.74 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL1772714 | 0.74 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL8339 | 0.74 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| Acridine SCHEMBL29352289 | 0.74 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL634894 | 0.73 | PARP1 (0.53) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL17897155 | 0.72 | APP (0.49) | TRPA1CA1CA2ITGB2ICAM1 | |
| Acridine SCHEMBL29200445 | 0.72 | MAPT (0.83) | ALDH1A1HPGDMAPTGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010707-B | Process for preparing quinoline pyrrole derivatives | 淮阴师范学院 | 2023-09-19 | — | — | CN | claimed |
| CN-115010707-A | Process for preparing quinolopyrrole derivatives | 淮阴师范学院 | 2022-09-06 | — | — | CN | claimed |
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-11780838-B1 | Pyrrolo[3,2-b]quinoline compounds as antibacterial agents | King Faisal University (SA) | 2023-10-10 | — | — | US | disclosed |
| US-11780838-B1 | Pyrrolo[3,2-b]quinoline compounds as antibacterial agents | King Faisal University (SA) | 2023-10-10 | — | — | US | disclosed |
| CN-115010707-B | Process for preparing quinoline pyrrole derivatives | 淮阴师范学院 | 2023-09-19 | — | — | CN | disclosed |
| CN-115010707-A | Process for preparing quinolopyrrole derivatives | 淮阴师范学院 | 2022-09-06 | — | — | CN | disclosed |
| CN-103254108-B | Preparation method of multifunctional pyrrole and pyrrolo [3,4-C ] quinoline | UNIV SOOCHOW | 2015-06-10 | — | — | CN | disclosed |
| CN-103254108-A | New preparation method of multifunctional pyrrole and pyrrolo [3,4-C ] quinoline | UNIV SOOCHOW | 2013-08-21 | — | — | CN | disclosed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780838-B1 | Pyrrolo[3,2-b]quinoline compounds as antibacterial agents | POLB, TOP2A, POLR2B | ALDH1A1 3816/4885HPGD 972/4885MAPT 3559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.