SCHEMBL6016299

SCHEMBL6016299

O=C(CBr)OO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL100137 0.74
SCHEMBL8442017 0.71 TRPA1 (0.63)
SCHEMBL4158637 0.71
SCHEMBL38893 0.69 TSHR (0.47)
SCHEMBL7907029 0.69
SCHEMBL25435249 0.69
SCHEMBL1331006 0.69
SCHEMBL6959521 0.69
SCHEMBL6960741 0.69
SCHEMBL12305774 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1902175-B Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XENOPORT INC 2012-08-22 CN claimed
CN-101486668-B Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XENOPORT INC 2014-07-02 CN disclosed
CN-102702065-A Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XENOPORT INC 2012-10-03 CN disclosed
CN-1902175-B Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XENOPORT INC 2012-08-22 CN disclosed
CN-101486668-A Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XENOPORT INC (US) 2009-07-22 CN disclosed
CN-1902175-A Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XENOPORT INC (US) 2007-01-24 CN disclosed
EP-1137672-B2 CARBOHYDRATE OXIDATION PRODUCTS AND DERIVATIVES TNO (NL) 2006-12-20 EP disclosed
EP-1137672-B1 CARBOHYDRATE OXIDATION PRODUCTS AND DERIVATIVES NL ORGANISATIE VOORTOEGEPAST N (NL) 2004-01-07 EP disclosed
EP-1137672-A1 CARBOHYDRATE OXIDATION PRODUCTS AND DERIVATIVES NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2001-10-04 EP disclosed
WO-2000026257-A1 CARBOHYDRATE OXIDATION PRODUCTS AND DERIVATIVES NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETEN - SCHAPPELIJK ONDERZOEK TNO (NL) 2000-05-11 WO disclosed
EP-0999222-A1 Carbohydrate oxidation products NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2000-05-10 EP disclosed