⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708769 | 0.75 | — | — | |
| SCHEMBL100137 | 0.72 | — | — | |
| SCHEMBL7627037 | 0.72 | TSHR (0.44) | — | |
| SCHEMBL3985200 | 0.72 | — | — | |
| SCHEMBL223029 | 0.69 | — | — | |
| SCHEMBL8442017 | 0.69 | TRPA1 (0.63) | — | |
| SCHEMBL4158637 | 0.69 | — | — | |
| SCHEMBL6016299 | 0.69 | — | — | |
| SCHEMBL6073705 | 0.69 | — | — | |
| SCHEMBL11856188 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023170699-A1 | TRICYCLIC SPIRO[CHROMANE-2,4'-PIPERIDIN]-4(3H)-ONE WITH 1,3,4-OXADIAZOLE LINKERS COMPOSITIONS AND PROCESS FOR PREPARATION THEREOF. | GHATPANDE NITIN (IN) | 2023-09-14 | — | — | WO | claimed |
| US-20240196929-A1 | Using fruit oil immersion including Olea europaea Olive oil varietals to preserve and stabilize Bromoform products from the red seaweed Asparagopsis armata and Asparagopsis taxiformis applied as a livestock feed supplement to reduce enteric methane | BASON ROGER PETERS GARTH (US) | 2024-06-20 | — | — | US | disclosed |
| WO-2023170699-A1 | TRICYCLIC SPIRO[CHROMANE-2,4'-PIPERIDIN]-4(3H)-ONE WITH 1,3,4-OXADIAZOLE LINKERS COMPOSITIONS AND PROCESS FOR PREPARATION THEREOF. | GHATPANDE NITIN (IN) | 2023-09-14 | — | — | WO | disclosed |