Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | DAO | P14920 | 1/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.70 |
| ▸ | CES1 | P23141 | 5/20 | 0.58 |
| ▸ | CES2 | O00748 | 4/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1902823 | 0.91 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL27916115 | 0.90 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL21599098 | 0.90 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28693411 | 0.90 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28601772 | 0.90 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL9705228 | 0.90 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2400344 | 0.90 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL31376992 | 0.90 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11453164 | 0.89 | TSHR (0.61) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL10948080 | 0.88 | TSHR (0.67) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137395-B1 | A STORAGE TANK BOTTOM CORROSION PROTECTION SYSTEM | NORTHERN TECH INTERNATIONAL CORPORATION (US) | 2019-04-24 | — | — | EP | claimed |
| EP-3137395-A1 | A STORAGE TANK BOTTOM CORROSION PROTECTION SYSTEM | Northern Technologies International Corporation (US) | 2017-03-08 | — | — | EP | claimed |
| US-9556635-B2 | Storage tank bottom corrosion protection system | NORTHERN TECHNOLOGIES INTERNATIONAL CORPORATION (US) | 2017-01-31 | — | — | US | claimed |
| US-9365596-B2 | Method for preparing quaternary phosphonium salts | MICROVAST POWER SYSTEMS CO., LTD. (CN) | 2016-06-14 | — | — | US | claimed |
| US-20150307256-A1 | STORAGE TANK BOTTOM CORROSION PROTECTION SYSTEM | NORTHERN TECHNOLOGIES INTERNATIONAL CORPORATION | 2015-10-29 | — | — | US | claimed |
| US-20150166587-A1 | METHOD FOR PREPARING QUATERNARY PHOSPHONIUM SALTS | MICROVAST POWER SYSTEMS CO., LTD. (CN) | 2015-06-18 | — | — | US | claimed |
| US-20120275951-A1 | System for Decreasing Environmental Corrosion Factors and/or for Delivering One or More Corrosion Inhibiting Compounds to an Enclosure | NORTHERN TECHNOLOGIES INTERNATIONAL CORPORATION (US) | 2012-11-01 | — | — | US | claimed |
| US-20120040151-A1 | RUST-RESISTANT TAPE | NORTHERN TECHNOLOGIES INTERNATIONAL CORPORATION (US) | 2012-02-16 | — | — | US | claimed |
| US-7745592-B2 | Cumate-inducible expression system for eukaryotic cells | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2010-06-29 | — | — | US | claimed |
| EP-1385946-B1 | A SYSTEM FOR INDUCIBLE EXPRESSION IN EUKARYOTIC CELLS | CA NAT RESEARCH COUNCIL (CA) | 2009-12-23 | — | — | EP | claimed |
| US-5630904-A | Stripping and cleaning agent for removing dry-etching and photoresist residues from a semiconductor substrate, and a method for forming a line pattern using the stripping and cleaning agent | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1997-05-20 | — | — | US | claimed |
| EP-0662527-B1 | Vapor phase corrosion inhibitor-desiccant material | CORTEC CORP (US) | 1997-05-14 | — | — | EP | claimed |
| US-5466858-A | Ruthenium catalyst, high selectivity with a carboxylic acid | UBE INDUSTRIES, LTD. (JP) | 1995-11-14 | — | — | US | claimed |
| EP-0680078-A2 | Semiconductor substrate surface treatment | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-11-02 | — | — | EP | claimed |
| EP-0662527-A1 | Vapor phase corrosion inhibitor-desiccant material | CORTEC CORPORATION (US) | 1995-07-12 | — | — | EP | claimed |
| US-5422187-A | Using anhydrous amine molybdate mixed with amine benzoates, amine nitrates and benzotraiazole desiccants; protective coatings | CORTEC CORPORATION (US) | 1995-06-06 | — | — | US | claimed |
| EP-0653454-A1 | Anti-corrosion plastic film containing recycled resin | CORTEC CORPORATION (US) | 1995-05-17 | — | — | EP | claimed |
| US-5393457-A | Sodium nitrate, benzotriazole, an anhydrous molybdate; silica gel particles; a substrate which comprises a foam; protective devices or coatings | MIKSIC BORIS A (US) | 1995-02-28 | — | — | US | claimed |
| US-5344589-A | Silica gel particles coated with molybdate salt, benzotriazole, sodium nitrite | CORTEC CORPORATION (US) | 1994-09-06 | — | — | US | claimed |
| US-5332525-A | Vapor phase corrosion inhibitor-desiccant material | CORTEC CORPORATION (US) | 1994-07-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166587-A1 | METHOD FOR PREPARING QUATERNARY PHOSPHONIUM SALTS | PHPT1, PHOSPHO1, PTEN | TSHR 2677/4885DAO 1566/4885NAPRT 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.